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Eurasian avian-like H1N1(EA H1N1)swine influenza virus(SIV)outside European countries was first detected in Hong Kong Sp......
Hepatitis C virus(HCV)affects 130-210 million people worldwide and is one of the major risk factors for hepatocellular c......
AIM: The role of hepatitis B virus (HBV) genotypes on the clinical features and prognosis of patients with hepatocellula......
AIM: To investigate the genetic background of human defensin expression in type 1 and 2 diabetes.METHODS: Associations b......
目的探讨金华市人民医院门诊女性宫颈上皮细胞人乳头瘤病毒(HPV)的感染情况及亚型分布情况。方法采用基因芯片法对就诊的妇女进行2......
AIM: To establish whether virulence factor genes vacA and cagA are present in Helicobacter pylori (H. pylori) retrieved ......
AIM: To investigate the molecular mechanism for regulation of cholesterol metabolism by hepatitis C virus(HCV) core prot......
Hepatitis C virus(HCV) infection induces steatosis and is accompanied by multiple metabolic alterations including hyperu......
Genetic Analysis of the VP1 Region of Human Enterovirus 71 Strains Isolated in Fuyang,China,During 2
Enterovirus 71(EV71) is a common cause of Hand,foot,and mouth disease(HFMD) and may also cause severe neurological disea......
Utilizing restriction endonuclease mapping and blot bybridization, we have determined the arrangement of the α-globin ......
AIM:To evaluate effects of UDP-glucuronosyltransferase1A1(UGT1A1) and thymidylate synthetase(TS) gene polymorphisms on i......
Association between CHRNA3 rs1051730 Genotype and Lung Cancer Risk in Chinese Han Population:A Case-
Recent population-based genome wide association studies have revealed potential susceptibility loci of lung cancer at th......
,Arylamine N-acetyltransferase 2 genotype-dependent N-acetylation of isoniazid in cryopreserved huma
Cryopreserved human hepatocytes were used to investigate the role of arylamine Nacetyltransferase 2 (NAT2;EC 2.3.1.5) po......
Hepatocellular carcinoma(HCC) is one of the most common causes of cancer-related death worldwide. Chronic infection of h......
Association between CYP24A1 polymorphisms and the risk of colonic polyps and colon cancer in a Chine
AIM To determine the pathogenesis and potential single nucleotide polymorphisms(SNPs) as screening sites for colonic pol......
Mapping epistasis and environment × QTX interaction based on four-omics genotypes for the detected Q
Using newly developed methods and software, association mapping was conducted for chromium content and total sugar in to......
Genotyping for Kidd, Kell, Duffy, Scianna, and RHCE blood group antigens polymorphisms in Jiangsu Ch
Background Molecular testing is more precise compared to serology and has been widely used in genotyping blood group ant......
Oculocutaneous albinism(OCA)is an autosomal recessive disorder characterized by hypopigmentation in eyes,hair and skin,a......
目的研究福建省长乐市结核分枝杆菌临床分离株的基因型构成、主要流行株及其相关传播流行特征。方法选择15个可变数目串联重复序列......
Objective To confirm the genetic relation between Giardia lamblia (G. lamblia) isolates from different geographic regio......
目的 初步探讨MLVA(multiple-locus variable-number tandem-repeat analysis)技术在黄疸出血群钩端螺旋体基因分型中的应用.方法 ......
目的 建立ABO基因5非翻译区(5untranslated region,5-UTR)长片段的序列分析方法,研究5UTR的基因多态性,为揭示ABO基因上游转录调控......
Genotyping for Kidd, Kell, Duffy, Scianna, and RHCE blood group antigens polymorphisms in Jiangsu Ch
Background Molecular testing is more precise compared to serology and has been widely used in genotyping blood group ant......
目的:探讨中国广东汉族群体血管紧张素转换酶基因(ACE)第16内含子中287bp片段的插入/缺失多态性分布。方法:应用PCR扩增技术检测244名广东籍汉族人ACE基因型......
目的采用Meta分析评价拉米夫定治疗B/C基因型乙肝病毒的疗效及其相关性。方法检索CNKI(1966~2013);Medline(1966~2013)、Pubmed(19......
目的了解下呼吸道标本中肺炎克雷伯菌耐药特点及产超广谱β内酰胺酶(ESBLs)肺炎克雷伯菌的检出率、基因型特点.方法收集下呼吸道标......
[目的]选用目前新药遗传毒性评价中推荐使用的3种试验方法(小鼠骨髓微核试验、鼠伤寒沙门氏菌回复突变试验、体外CHL细胞染色体畸变......
目的 探讨产超广谱β-内酰胺酶(extended-spectrum β-lactamases,ESBLs)大肠埃希菌的分子流行病学及对常用抗菌药物的耐药情况。方法......
目的 探讨桂西地区临床分离鲍曼不动杆菌的耐药情况和碳青霉烯耐药菌株的β-内酰胺酶基因分型,为临床抗感染治疗和耐药性控制提供......
目的了解胆道感染大肠埃希菌的耐药性及ESBLs基因型分布状况。方法采用纸片扩散法(K—B法)对大肠埃希菌进行抗菌药物的敏感性试验,通......
目的探讨临床分离的多药耐药鲍氏不动杆菌AmpC酶活性及基因型。方法AmpC酶活性检测采用三维法、三联纸片法;基因检测采用PCR法。结......
目的探讨HCV基因分型、甲胎蛋白异质体(AFP-L3)和P53抗体联合检测在HCV相关肝细胞癌(HCV-HCC)中的诊断价值。方法选取2016年1月-20......
目的分析2型糖尿病(T2DM)人群中乙醛脱氢酶2(ALDH2)基因Glu504Lys多态性的分布特点,探讨ALDH2基因504位点基因突变与空腹血糖、HbA......
目的对人工培植的蝉花孢梗束进行毒理学研究,评价其口服安全性。方法利用急性毒性试验、体外中国仓鼠肺细胞染色体畸变试验、骨髓......
以雌褐牙鲆(Paralichthys olivaceus)、雄夏鲆(P. dentatus)及其子一代为研究对象,对其核糖体基因的ITS1序列进行比较分析。结果表明, IT......
采用AFLP指纹图谱3分析技术对来自我国不同地区的95株斜茎黄芪 瘤菌及24株已知根瘤菌的参比菌一起进行遗传多样性研究,结果表明,在50%相似性水平......
为了解北京地区人呼吸道合胞病毒(human respiratory syncytial virus,HRSV)的遗传变异和分子流行病学特征,首次对北京地区2003~200......
为探讨肠道细菌基因间重复序列(ERIC)的聚合酶链反应(PCR)技术用于副猪嗜血杆菌基因分型的可行性,对分离自广西地区不同猪场的22株副猪......
AIM:To molecularly characterize hepatitis B virus(HBV)isolates from Kerala and to relate them to the clinical manifestat......
The present review describes the current status of multiplex quantitative real time polymerase chain reaction(q PCR) ass......
目的 了解珠海地区妇幼保健院产超广谱β-内酰胺酶(ESBLs)大肠埃希菌基因特点.方法 收集珠海地区两家妇幼保健院临床分离的316株大肠......
目的观察IL-18基因型及血清IL-18水平与糖尿病肾病(DN)的相关性,探讨DN的发病机制。方法采用聚合酶链反应-限制性片段长度多态性技术,......
目的:探讨马拉色菌属在临床疾病中的意义.方法:利用RAPD对临床分离株进行基因分型,建立马拉色菌属带型关系树状图,分析与相关疾病......
目的探讨中国云南汉族SLE患者与FcγRⅢA-158V/F基因多态性的相关性.方法采用聚合酶链式反应(PCR)与限制性片段长度多态性分析方法......
研究多基因座复等位基因的自交群体后代基因型频率,给出其递推算法,结果发现多个基因座都是纯合基因的基因型频率逐代增加,相对增......
以两个玉米 (ZeamaysL .)自交系原引 1号(YY1)和综 3 1(Z3 1)为研究材料 ,采用盆栽土培的培养方法 ,在正常供氮 (HN ,0 .15gN/kg干......
目的肾素基因错义突变与原发性高血压的相关性.方法运用聚合酶链反应-限制性片段长度多态性(PCR-RFLP)确定外显子9上的引起氨基酸......
利用一步法RT-PCR技术成功扩增了37个新城疫病毒分离株的(其中2株属于鸽源病毒)F基因片段(约500bp),通过对分离株的测序和基因分型......
目的研究池州地区分离的大肠埃希菌(E.coli)和肺炎克雷伯菌(K.pn)质粒编码的产超广谱β-内酰胺酶(ES-BLs)基因分布情况。方法收集大肠埃......
[目的]探讨天津口岸出人境人员乙型肝炎病毒(HBV)的基因类型分布特征。[方法]调查天津口岸出入境人员HBV血清学指标,采用实时荧光定量......